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35661-39-3 - N-Fmoc-L-alanine, 95% - Fmoc-Ala-OH - N-(9-Fluorenylmethoxycarbonyl)-L-alanine - H59438 - Alfa Aesar

H59438 N-Fmoc-L-alanine, 95%

CAS Number
35661-39-3
Synonyms
Fmoc-Ala-OH
N-(9-Fluorenylmethoxycarbonyl)-L-alanine

Size Price ($) Quantity Availability
5g 26.20
25g 90.90
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N-Fmoc-L-alanine, 95%

MDL
MFCD00037139
EINECS
252-660-6

Chemical Properties

Formula
C18H17NO4
Formula Weight
311.34
Melting point
147-153°
Solubility
Soluble in water.

Applications

N-Fmoc-L-alanine is potentially useful for proteomics studies and solid phase peptide synthesis techniques. Alanine is one of the simplest amino acids - a methyl group as the side chain. This small side chain confers a high degree of flexibility when incorporated into a polypeptide chain. The Fmoc group is typically removed with a base such as pyridine - an orthogonal de-protection strategy to the acid labilie Boc group.

Notes

Keep container tightly closed. Store away from oxidizing agents.

Literature References

Roger M. Freidinger.; Jeffery S. Hinkle.; Debra S. Perlow. Synthesis of 9-fluorenylmethyloxycarbonyl-protected N-alkyl amino acids by reduction of oxazolidinones. J. Org. Chem. 1983, 48, (1), 77-81.

Shu-Li You.; Jeffery W. Kelly. Total synthesis of didmolamides A and B. Tetrahedron Letters. 2005, 46, (15), 2567-2570.

GHS Hazard and Precautionary Statements

Precautionary Statements: P260-P201-P280-P304+P340-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
2225975
Harmonized Tariff Code
2924.29
TSCA
No

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