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H59711 N-Fmoc-1-trityl-L-histidine, 98%

CAS Number
109425-51-6
Synonyms
Fmoc-His(Trt)-OH

Stock No. Size Price ($) Quantity Availability
H59711-06 5g 42.50
H59711-14 25g 147.00
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N-Fmoc-1-trityl-L-histidine, 98%

MDL
MFCD00043332
EINECS
439-640-4

Chemical Properties

Formula
C40H33N3O4
Formula Weight
619.71
Melting point
145°
Storage & Sensitivity
Keep Cold. Moisture Sensitive. Store under Argon.
Solubility
Slightly soluble in water.

Applications

It is used in the synthesis and application of Fmoc-His(3-Bum)-OH.

Notes

Moisture sensitive. Store away from water/moisture and oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Store under inert gas. Protect from heat. Keep it refrigerated.

Literature References

Peter Sieber, et al. Protection of histidine in peptide synthesis: A Reassessment of the trityl group.Tetrahedron Lett.,1987,28(48), 6031-6034.

M. Mergler, et al. Synthesis and Application of Fmoc-His(3-Bum)-OH.Journal of Peptide Science.,2001,7(9), 502-510.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
5204720
Harmonized Tariff Code
2933.29
TSCA
No

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