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It could react with 1,2,3-trimethoxy-benzene, and obtain the 4-oxo-4-(2,3,4-trimethoxy-phenyl)-butyric acid methyl ester. This reaction needs the reagent of PPA. Butanedioic Acid 1-Methyl Ester is an intermediate in the synthesis of agonist to both GHB and GABAB neural receptors, exhibiting neurotransmitter-like effects.
Ryszard Andruszkiewicz, et al. Synthesis of N3-fumaramoyl-L-2,3-diaminopropanoic acid analogues, the irreversible inhibitors of glucosamine synthetase.Int. J. Pept. Protein Res.,1986,27(5), 449-453.
P Borgeat, et al. Transformation of arachidonic acid and homo-gamma-linolenic acid by rabbit polymorphonuclear leukocytes. Monohydroxy acids from novel lipoxygenases.J. Biol. Chem.,1976,2527816-7820.