I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.
N-(3,5-dichlorophenyl)benzenesulfonamide (C21) as an inhibitor of Rac activation by Dock5.
Thomas D. Penning .; John J. Talley.; Stephen R. Bertenshaw.; Jeffery S. Carter.; Paul W. Collins.; Stephen Docter.; Matthew J. Graneto.; Len F. Lee .; James W. Malecha.; Julie M. Miyashiro.; Roland S. Rogers.; D. J. Rogier .; Stella S. Yu.; Gary D. Anderson.; Earl G. Burton.; J. Nita Cogburn.; Susan A. Gregory.; Carol M. Koboldt.; William E. Perkins.; Karen Seibert.; Amy W. Veenhuizen.; Yan Y. Zhang.; Peter C. Isakson. Synthesis and Biological Evaluation of the 1,5-Diarylpyrazole Class of Cyclooxygenase-2 Inhibitors:? Identification of 4-[5-(4-Methylphenyl)-3- (trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide (SC-58635, Celecoxib). J. Med. Chem. 1997, 40 (9),1347-1365.
German L. Perlovich.;Nadezda N. Strakhov.; Vladimir P. Kazachenko.; Tatyana V. Volkova.; Valery V. Tkachev.; Klaus-Jurgen Schaper.; Oleg A. Raevsky. Sulfonamides as a subject to study molecular interactions in crystals and solutions: Sublimation, solubility, solvation, distribution and crystal structure. Int. J. Pharm. 2008, 349 (1-2),300-313.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant