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Dimethylthiocarbamoyl chloride is used as an intermediate in the synthesis of pharmaceuticals. It finds application in chemoselective deoxygenation of pyridine-N-oxides. It is also used as a starting reagent in the synthesis of dimethylthiocarbamates.
Zaim, O.; Tuzun, N. S.; Cevik, B.; Ozcan, H.; Boz, E. Synthesis, reactions and DFT study of tropolone N,N-dimethylthiocarbamate. Tetrahedron 2015, 71 (33), 5391-5398.
Gandhi, M. R.; Yamada, M.; Kondo, Y.; Sato, R.; Hamada, F. Synthesis and Characterization of Dimethylthiocarbamoyl-Modified Thiacalix[n]arenes for Selective Pd(II)-Ion Extraction. Ind. Eng. Chem. Res. 2014, 53 (7), 2559-2565.
Hazard Statements: H314-H317-H350
Causes severe skin burns and eye damage. May cause an allergic skin reaction. May cause cancer.
Precautionary Statements: P201-P202-P260-P264b-P272-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P308+P313-P310-P363-P501c
Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Contaminated work clothing should not be allowed out of the workplace. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or concerned: Get medical advice/attention. Immediately call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant