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31519-22-9 - 1,4-Dihydroxy-2-naphthoic acid, 98% - H60210 - Alfa Aesar

H60210 1,4-Dihydroxy-2-naphthoic acid, 98%

CAS Number

Size Price ($) Quantity Availability
5g 10.35
25g 41.84
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1,4-Dihydroxy-2-naphthoic acid, 98%


Chemical Properties

Formula Weight
Melting point
220° dec.
Slightly soluble in water.


1,4-Dihydroxy-2-naphthoic acid from Propionibacterium freudenreichii is known to promote the proliferation of Bifidobacterium. It has potential therapeutic application for psoriasis treatment.


Stable under recommended storage conditions. Incompatible with oxidizing agents.

Literature References

Yoshikiyo Okada; Yoshikazu Tsuzuki; Kazuyuki Narimatsu; Hirokazu Sato; Toshihide Ueda; Hideaki Hozumi; Shingo Sato; Ryota Hokari; Chie Kurihara; Shunsuke Komoto; Chikako Watanabe; Kengo Tomita; Atsushi Kawaguchi; Shigeaki Nagao; Soichiro Miura. 1,4-Dihydroxy-2-naphthoic acid from Propionibacterium freudenreichii reduces inflammation in interleukin-10-deficient mice with colitis by suppressing macrophage-derived proinflammatory cytokines. Journal of Leukocyte Biology. 2013, 94,(3), 473-480.


Chong-Fai Mok; Chuan-Ming Xie; Kathy Wai-Yan Sham; Zhi-Xiu Lin; Christopher Hon-Ki Cheng. 1,4-dihydroxy-2-naphthoic acid induces apoptosis in human keratinocyte: Potential application for psoriasis treatment. Evidence-based Complementary and Alternative Medicine. 2013, 2013,792840.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

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