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H60230 2,4-Dibromothiazole, 97%

CAS Number

Stock No. Size Price ($) Quantity Availability
H60230-03 1g 42.40
H60230-06 5g 163.00
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2,4-Dibromothiazole, 97%


Chemical Properties

Formula Weight
Melting point
Storage & Sensitivity
Store under Nitrogen. Ambient temperatures.


2,4-Dibromothiazole is applied as a building block in a synthesis of Melithiazole C employing a highly (E)-selective cross-metathesis between the derived 4-vinylthiazole and a dienote side-chain. It is also used as an intermediate in the preparation of various 2,4-disubstituted thiazole derivatives with biologically active properties such as survival motor neuron (SMN) protein modulators.


Air sensitive. Incompatible with oxidizing agents.

Literature References

Julian Gebauer; Stellios Arseniyadis; Janine Cossy. A concise total synthesis of melithiazole C. Organic Letters. 2007, 9,(17), 3425-3427.


A.Spiess; G.Heckmann; T.Bach. Regio- and stereoselective synthesis of α-chiral 2-substituted 4-bromo-thiazoles from 2,4-dibromothiazole by bromine-magnesium exchange. Building blocks for the synthesis of thiazolyl peptides and dolabellin. Synlett. 2004, (1), 131-133.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H315-H318-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye damage. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P310-P312-P330-P332+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Rinse mouth. If skin irritation occurs: Get medical advice/attention. Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

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