Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

4175-77-3 - 2,4-Dibromothiazole, 97% - H60230 - Alfa Aesar

H60230 2,4-Dibromothiazole, 97%

CAS Number
4175-77-3
Synonyms

Size Price ($) Quantity Availability
1g 40.05
5g 157.55
Add to Cart Add to Quote Request View Item

2,4-Dibromothiazole, 97%

MDL
MFCD01318994

Chemical Properties

Formula
C3HBr2NS
Formula Weight
242.92
Melting point
80-84°

Applications

2,4-Dibromothiazole is applied as a building block in a synthesis of Melithiazole C employing a highly (E)-selective cross-metathesis between the derived 4-vinylthiazole and a dienote side-chain. It is also used as an intermediate in the preparation of various 2,4-disubstituted thiazole derivatives with biologically active properties such as survival motor neuron (SMN) protein modulators.

Notes

Air sensitive. Incompatible with oxidizing agents.

Literature References

Julian Gebauer; Stellios Arseniyadis; Janine Cossy. A concise total synthesis of melithiazole C. Organic Letters. 2007, 9,(17), 3425-3427.

 

A.Spiess; G.Heckmann; T.Bach. Regio- and stereoselective synthesis of α-chiral 2-substituted 4-bromo-thiazoles from 2,4-dibromothiazole by bromine-magnesium exchange. Building blocks for the synthesis of thiazolyl peptides and dolabellin. Synlett. 2004, (1), 131-133.

GHS Hazard and Precautionary Statements

Hazard Statements: H318-H315-H302-H335

Causes serious eye damage. Causes skin irritation. Harmful if swallowed. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P310-P362-P301+P312-P312-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Immediately call a POISON CENTER or doctor/physician. Take off contaminated clothing and wash before reuse. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2934.10
TSCA
No

Recommended

  • 00908

    Copper powder, -40+100 mesh, 99.5% (metals basis)
  • 11606

    Copper(I) iodide, 98%

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware