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H60274 O6-Benzylguanine, 98%

CAS Number

Stock No. Size Price ($) Quantity Availability
H60274-MD 250mg 42.70
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O6-Benzylguanine, 98%


Chemical Properties

Formula Weight
Storage & Sensitivity
Ambient temperatures.
Soluble in methanol (20 mg/ml), and aqueous alkali (Heated).


O6-Benzylguanine is an effective substrate and efficient inactivator of DNA alkyltransferase. O6-Benzylguanine is an inhibitor of MGMT. It is also used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.


Keep container tightly closed in a dry and well-ventilated place. Stable under recommended storage conditions. Keep away from strong oxidizing agents.

Literature References

ME Dolan.; RB Mitchell.; C Mummert.; RC Moschel. Effect of O6-benzylguanine analogues on sensitivity of human tumor cells to the cytotoxic effects of alkylating agents. Cancer research. 199175 (20), 29-35.

ME Dolan.; AE Pegg. O6-benzylguanine and its role in chemotherapy. Clinical Cancer Research. 19973 (1), 837-839.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Harmonized Tariff Code


  • A12470

    2-Vinylnaphthalene, 97%
  • A12667

    2',3'-Dichloroacetophenone, 98%
  • A15342

    4-n-Propylphenol, 98%
  • B21782

    Naphthalene-1-sulfonic acid hydrate, 98%
  • B24857

    6-Hydroxyhexanoic acid, 95%, may cont. variable amounts of dimer

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