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19916-73-5 - O6-Benzylguanine, 98% - H60274 - Alfa Aesar

H60274 O6-Benzylguanine, 98%

CAS Number

Size Price ($) Quantity Availability
250mg 40.20
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O6-Benzylguanine, 98%


Chemical Properties

Formula Weight
Soluble in methanol (20 mg/ml), and aqueous alkali (Heated).


O6-Benzylguanine is an effective substrate and efficient inactivator of DNA alkyltransferase. O6-Benzylguanine is an inhibitor of MGMT. It is also used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.


Keep container tightly closed in a dry and well-ventilated place. Stable under recommended storage conditions. Keep away from strong oxidizing agents.

Literature References

ME Dolan.; RB Mitchell.; C Mummert.; RC Moschel. Effect of O6-benzylguanine analogues on sensitivity of human tumor cells to the cytotoxic effects of alkylating agents. Cancer research. 199175 (20), 29-35.

ME Dolan.; AE Pegg. O6-benzylguanine and its role in chemotherapy. Clinical Cancer Research. 19973 (1), 837-839.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code


  • A12470

    2-Vinylnaphthalene, 97%
  • A12667

    2',3'-Dichloroacetophenone, 98%
  • A15342

    4-n-Propylphenol, 98%
  • B21782

    Naphthalene-1-sulfonic acid hydrate, 98%
  • B24857

    6-Hydroxyhexanoic acid, 95%, may cont. variable amounts of dimer

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