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2634-33-5 - 1,2-Benzisothiazol-3-one, 97% - H60492 - Alfa Aesar

H60492 1,2-Benzisothiazol-3-one, 97%

CAS Number
2634-33-5
Synonyms

Size Price ($) Quantity Availability
5g 69.30
25g 264.00
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1,2-Benzisothiazol-3-one, 97%

MDL
MFCD00127753
EINECS
220-120-9

Chemical Properties

Formula
C7H5NOS
Formula Weight
151.19
Melting point
154-158°
Solubility
Soluble in dichloromethane, dimethyl sulfoxide, methanol.

Applications

It is an antimicrobial agent and a pharmaceutical intermediate.

Notes

Store at room temperature. Keep away from oxidizing agents.

Literature References

Keith D. Combrink .; H. Belgin Gülgeze.; Nicholas A. Meanwell .; Bradley C. Pearce.; Pi Zulan .; Gregory S. Bisacchi.; Daniel G. M. Roberts.; Paul Stanley.; Steven M. Seiler. 1,2-Benzisothiazol-3-one 1,1-Dioxide Inhibitors of Human Mast Cell Tryptase. J. Med. Chem. 1998, 41 (24),4854-4860.

Magid Abou-Gharbia.; John A. Moyer.; Usha Patel.; Michael Webb.; Guy Schiehser.; Terrance Andree.; J. Thomas Haskins. Synthesis and structure-activity relationship of substituted tetrahydro- and hexahydro-1,2-benzisothiazol-3-one 1,1-dioxides and thiadiazinones: potential anxiolytic agents. J. Med. Chem. 1989, 32 (5),1024-1033.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H315-H318-H317

Harmful if swallowed. Causes skin irritation. Causes serious eye damage. May cause an allergic skin reaction.

Precautionary Statements: P261-P280a-P305+P351+P338-P310a-P301+P312a-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Hazard Class
9
Packing Group
III
Harmonized Tariff Code
2934.99
TSCA
No
RTECS
DE4620000

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