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It is an antimicrobial agent and a pharmaceutical intermediate.
Keith D. Combrink .; H. Belgin Gülgeze.; Nicholas A. Meanwell .; Bradley C. Pearce.; Pi Zulan .; Gregory S. Bisacchi.; Daniel G. M. Roberts.; Paul Stanley.; Steven M. Seiler. 1,2-Benzisothiazol-3-one 1,1-Dioxide Inhibitors of Human Mast Cell Tryptase. J. Med. Chem. 1998, 41 (24),4854-4860.
Magid Abou-Gharbia.; John A. Moyer.; Usha Patel.; Michael Webb.; Guy Schiehser.; Terrance Andree.; J. Thomas Haskins. Synthesis and structure-activity relationship of substituted tetrahydro- and hexahydro-1,2-benzisothiazol-3-one 1,1-dioxides and thiadiazinones: potential anxiolytic agents. J. Med. Chem. 1989, 32 (5),1024-1033.
Hazard Statements: H302-H315-H317-H318
Harmful if swallowed. Causes skin irritation. May cause an allergic skin reaction. Causes serious eye damage.
Precautionary Statements: P261-P264b-P270-P272-P280-P301+P312-P302+P352-P305+P351+P338-P310-P330-P333+P313-P362-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Contaminated work clothing should not be allowed out of the workplace. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Rinse mouth. If skin irritation or rash occurs: Get medical advice/attention. Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant