Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

4521-28-2 - 4-(4-Methoxyphenyl)butyric acid, 98% - H60613 - Alfa Aesar

H60613 4-(4-Methoxyphenyl)butyric acid, 98%

CAS Number
4521-28-2
Synonyms

Size Price ($) Quantity Availability
1g 14.50
5g 59.20
Add to Cart Add to Quote Request View Item

4-(4-Methoxyphenyl)butyric acid, 98%

MDL
MFCD00004404
EINECS
224-849-3

Chemical Properties

Formula
C11H14O3
Formula Weight
194.23
Melting point
56-59°
Solubility
Slightly soluble in methanol. Insoluble in chloroform.

Applications

4-(4-Methoxyphenyl)butyric acid on demethylation with pyridinium hydrochloride affords 4-hydroxyphenylbutyric acid, a key starting material for the synthesis of preclinical candidate LY518674.

Notes

Store in a cool, dry place, in a well sealed container. Store away from oxidizing agents.

Literature References

Christopher R. Schmid; Christopher A. Beck; Jason S. Cronin and Michael A. Staszak. Demethylation of 4-Methoxyphenylbutyric Acid Using Molten Pyridinium Hydrochloride on Multikilogram Scale. Org. Proc. Res. Dev. 2004, 8 (4), 670-673.

Timothy P. Kogan; Brian Dupré, Huong Bui; Kathy L. McAbee; Jamal M. Kassir; Ian L. Scott; Xin Hu; Peter Vanderslice; Pamela J. Beck and Richard A. F. Dixon. Novel Synthetic Inhibitors of Selectin-Mediated Cell Adhesion:? Synthesis of 1,6-Bis[3-(3-carboxymethylphenyl)-4-(2-α-d-mannopyranosyloxy)phenyl]hexane (TBC1269). J. Med. Chem. 1998, 41 (7), 1099-1111.

Other References

Beilstein
2416568
Harmonized Tariff Code
2918.99
TSCA
No

Recommended

  • H31701

    4-Fluoro-3-(trifluoromethyl)benzenesulfonamide, 97%
  • H55528

    1,6-Bis(diphenylphosphino)hexane, 97%
  • L14619

    Isoprene, 99%, stab. with ca 0.02% 4-tert-butylcatechol
  • B23061

    Hexaphenylcyclotrisiloxane, 98+%
  • 39754

    Tin oxide, antimony doped, polymeric precursor, Oxide ≈ 30 wt%

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware