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88054-22-2 - 2-Methyl-5-nitroimidazole, 99% - H60614 - Alfa Aesar

H60614 2-Methyl-5-nitroimidazole, 99%

CAS Number
88054-22-2
Synonyms

Size Price ($) Quantity Availability
50g 22.70
250g 92.30
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2-Methyl-5-nitroimidazole, 99%

MDL
MFCD00151322
EINECS
211-790-3

Chemical Properties

Formula
C4H5N3O2
Formula Weight
127.10
Melting point
251-255°
Boiling Point
399°
Flash Point
195°(383°F)
Density
1.426
Solubility
Slightly soluble in ethanol, easily soluble in diluted acid and diluted alkali.

Applications

2-Methyl-4(5)-nitroimidazole was used to study the mechanism of both the alkaline and acidic hydrolysis of tinidazole. It is mainly used to synthesize intermediate of medicines such as Metronidazole and dimetridazole.

Notes

Store in a cool, dry place, in a well sealed container. Store away from oxidizing agents.

Literature References

Jukka-Pekka K Salo; Jari Yli-Kauhaluoma; Hannele Salomies. On the hydrolytic behavior of tinidazole, metronidazole, and ornidazole. Journal of Pharmaceutical Sciences. 2003, 92 (4), 739-746.

Y Henry; A Guissani, B Hickel. Radicals of nitroimidazole derivatives: pH dependence of rates of formation and decay related to acid-base equilibria. International journal of radiation biology and related studies in physics, chemistry, and medicine. 1987, 51 (5), 797-809.

GHS Hazard and Precautionary Statements

Hazard Statements: H302

Harmful if swallowed.

Precautionary Statements: P260u-P201-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
4032
Harmonized Tariff Code
2933.29
TSCA
No

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