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H60631 1H-Pyrazole-1-carboxamidine hydrochloride, 99%

CAS Number
4023-02-3
Synonyms
1-Amidinopyrazole hydrochloride
Praxadine

Stock No. Size Price ($) Quantity Availability
H60631-09 10g 45.00
H60631-18 50g 181.00
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1H-Pyrazole-1-carboxamidine hydrochloride, 99%

MDL
MFCD00210087
EINECS
429-520-1

Chemical Properties

Formula
C4H6N4•HCl
Formula Weight
146.58
Melting point
167-170°
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in water.

Applications

1H-Pyrazole-1-carboxamidine hydrochloride may be used in the following studies: • Preparation of guanidylated hollow fiber membranes. • Guanylation of amines and in peptide synthesis. • Synthesis of bis-guanidinium-cholesterol derivatives.

Notes

Incompatible with strong oxidizing agents. Store under room temperature.

Literature References

Michael S. Bernatowicz.; Youling Wu.; Gary R. Matsueda. 1H-Pyrazole-1-carboxamidine hydrochloride an attractive reagent for guanylation of amines and its application to peptide synthesis. J. Org. Chem. 1992, 57 (8),2497-2502.

Igor Slowing.; Brian G. Trewyn.; Victor S.-Y. Lin. Effect of Surface Functionalization of MCM-41-Type Mesoporous Silica Nanoparticles on the Endocytosis by Human Cancer Cells. J. Am. Chem. Soc. 2006, 128 (46),14792-14793.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H317-H318-H373

Harmful if swallowed. May cause an allergic skin reaction. Causes serious eye damage. May cause damage to organs through prolonged or repeated exposure.

Precautionary Statements: P260-P264b-P270-P272-P280-P301+P312-P302+P352-P305+P351+P338-P310-P314-P330-P333+P313-P363-P501c

Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Contaminated work clothing should not be allowed out of the workplace. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Get medical advice/attention if you feel unwell. Rinse mouth. If skin irritation or rash occurs: Get medical advice/attention. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Harmonized Tariff Code
2933.19
TSCA
No

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