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1H-Pyrazole-1-carboxamidine hydrochloride may be used in the following studies: Preparation of guanidylated hollow fiber membranes. Guanylation of amines and in peptide synthesis. Synthesis of bis-guanidinium-cholesterol derivatives.
Michael S. Bernatowicz.; Youling Wu.; Gary R. Matsueda. 1H-Pyrazole-1-carboxamidine hydrochloride an attractive reagent for guanylation of amines and its application to peptide synthesis. J. Org. Chem. 1992, 57 (8),2497-2502.
Igor Slowing.; Brian G. Trewyn.; Victor S.-Y. Lin. Effect of Surface Functionalization of MCM-41-Type Mesoporous Silica Nanoparticles on the Endocytosis by Human Cancer Cells. J. Am. Chem. Soc. 2006, 128 (46),14792-14793.
Hazard Statements: H302-H317-H318-H373
Harmful if swallowed. May cause an allergic skin reaction. Causes serious eye damage. May cause damage to organs through prolonged or repeated exposure.
Precautionary Statements: P260-P264b-P270-P272-P280-P301+P312-P302+P352-P305+P351+P338-P310-P314-P330-P333+P313-P363-P501c
Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Contaminated work clothing should not be allowed out of the workplace. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Get medical advice/attention if you feel unwell. Rinse mouth. If skin irritation or rash occurs: Get medical advice/attention. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant