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15641-58-4 - 2,2,3,3-Tetramethylcyclopropanecarboxylic acid, 97% - H60809 - Alfa Aesar

H60809 2,2,3,3-Tetramethylcyclopropanecarboxylic acid, 97%

CAS Number
15641-58-4
Synonyms

Size Price ($) Quantity Availability
1g 27.81
5g 113.34
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2,2,3,3-Tetramethylcyclopropanecarboxylic acid, 97%

MDL
MFCD00011538

Chemical Properties

Formula
C8H14O2
Formula Weight
142.20
Melting point
120-121°
Solubility
Slightly soluble in water. Soluble in methanol, ethanol and acetonitrile.

Applications

2,2,3,3-Tetramethylcyclopropanecarboxylic acid is used to start synthesis of central nervous system-active compounds.

Notes

Keep container tightly sealed. Store in refrigerated conditions. Incompatible with oxidizing agents.

Literature References

Eyal Sobol.; Meir Bialer.; Boris Yagen. Tetramethylcyclopropyl Analogue of a Leading Antiepileptic Drug, Valproic Acid. Synthesis and Evaluation of Anticonvulsant Activity of Its Amide Derivatives. J. Med. Chem. 2004, 47 (17), 4316-4326.

Neta Pessah.; Meir Bialer.; Bogdan Wlodarczyk.; Richard H. Finnell.; Boris Yagen. α-Fluoro-2,2,3,3-Tetramethylcyclopropanecarboxamide, a Novel Potent Anticonvulsant Derivative of a Cyclic Analogue of Valproic Acid. J. Med. Chem. 2009, 52 (8), 2233-2242.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2916.20
TSCA
No
RTECS
GZ2083500

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