Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

H61778 Tri(1-aziridinyl)phosphine sulfide, 98%

CAS Number
52-24-4
Synonyms
Triethylenethiophosphoramide
Thio-TEPA

Stock No. Size Price ($) Quantity Availability
H61778-03 1g 107.00
H61778-06 5g 492.00
Add to Cart Add to Quote Request View Item

Tri(1-aziridinyl)phosphine sulfide, 98%

MDL
MFCD00145452
EINECS
200-135-7

Chemical Properties

Formula
C6H12N3PS
Formula Weight
189.22
Storage & Sensitivity
Keep Cold.
Solubility
Soluble in benzene, acetone and methanol.

Applications

Tri(1-aziridinyl)phosphine sulfide is useful for the treatment of cancers, especially cancers resistant to chemotherapy. Antineoplastic. Thio-TEPA (N,N’N’-triethylenethiophosphoramide) is used as a cancer chemotherapeutic, alkylating agent. It is used to treat various kinds of cancer such as breast, ovarian and bladder cancer. It is also used as conditioning treatment prior to hematopoietic progenitor cell transplantation (HPCT)

Notes

Store in cool, well ventilated area. Keep container tightly closed. Store away from oxidizing agent.

Literature References

Craig Knox et. al. DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Research. 2011, 39(3), D1035-D1041.

A J Wyrobek; and W R Bruce. Chemical induction of sperm abnormalities in mice. Proceedings of the National Academy of Sciences of the United States of America. 1975, 72(11), 4425-4429.

GHS Hazard and Precautionary Statements

Hazard Statements: H300-H340-H350-H500

Fatal if swallowed. May cause genetic defects. May cause cancer. May form combustible dust concentrations in air

Precautionary Statements: P201-P202-P264b-P270-P281-P301+P310-P308+P313-P330-P501c

Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use personal protective equipment as required. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF exposed or concerned: Get medical advice/attention. Rinse mouth. Dispose of contents/ container to an approved waste disposal plant

Other References

Hazard Class
6.1
Packing Group
II
Harmonized Tariff Code
2933.99
TSCA
No
RTECS
SZ2975000

Recommended

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware