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31224-43-8 - 3-Fluoropyridine-2-carboxaldehyde, 98% - 3-Fluoro-2-formylpyridine - 3-Fluoropicolinaldehyde - H61902 - Alfa Aesar

H61902 3-Fluoropyridine-2-carboxaldehyde, 98%

CAS Number
31224-43-8
Synonyms
3-Fluoro-2-formylpyridine
3-Fluoropicolinaldehyde

Size Price ($) Quantity Availability
250mg 28.20
1g 84.70
5g 339.00
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3-Fluoropyridine-2-carboxaldehyde, 98%

MDL
MFCD07781234

Chemical Properties

Formula
C6H4FNO
Formula Weight
125.10
Solubility
Slightly soluble in water.

Applications

3-Fluoropyridine-2-carboxaldehyde is used to prepare taxoids derived from 9β-dihydrobaccatin-9,10-acetals with anti-tumor activities. It is also an intermediate used to synthesize S-3578 derivatives with potent activities against both methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa.

Notes

Store in cool, well ventilated area. Keep container tightly closed. Store away from oxidizing agent.

Literature References

Christopher M. Timperley; R. Eric Banks; Ian M. Young; Robert N. Haszeldine. Synthesis of some fluorine-containing pyridinealdoximes of potential use for the treatment of organophosphorus nerve-agent poisoning. Journal of Fluorine Chemistry. 2011, 132(8), 541-547.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2933.39
TSCA
No

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