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H62110 Methyl 3-oxocyclobutanecarboxylate, 97%

CAS Number
3-Oxocyclobutanecarboxylic acid methyl ester

Stock No. Size Price ($) Quantity Availability
H62110-MD 250mg 35.20
H62110-03 1g 105.00
H62110-06 5g 416.00
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Methyl 3-oxocyclobutanecarboxylate, 97%


Chemical Properties

Formula Weight
Storage & Sensitivity
Ambient temperatures.
Slightly soluble in water.


Methyl 3-oxocyclobutanecarboxylate can be used as an intermediate for the synthesis of various pharmaceutical compounds. It is used for the preparation of novel imidazobenzazepine derivatives as dual H1/5-HT2A antagonists for the treatment of sleep disorders.


Store in cool, well ventilated area. Keep container tightly closed. Store away from oxidizing agent.

Literature References

A. Bashir-Hashemi; J. R. Hardee; Nathan Gelber; Lida Qi; Theodore Axenrod. Regioselectivity in Photochemical Chlorocarbonylation of Carbonyl Compounds. J. Org. Chem. 1994, 59(8), 2132-2134.

Christian Stevens and Norbert De Kimpe. A New Entry into 2-Azabicyclo[2.1.1]hexanes via 3-(Chloromethyl)cyclobutanone. J. Org. Chem. 1996, 61(6), 2174-2178.

GHS Hazard and Precautionary Statements

Hazard Statements: H226-H317-H319

Flammable liquid and vapour. May cause an allergic skin reaction. Causes serious eye irritation.

Precautionary Statements: P210-P233-P240-P241-P242-P243-P264b-P272-P280-P303+P361+P353-P305+P351+P338-P333+P313-P363-P370+P378q-P501c

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Keep container tightly closed. Ground/bond container and receiving equipment. Use explosion-proof electrical/ventilating/lighting/ equipment. Use only non-sparking tools. Take precautionary measures against static discharge. Wash face, hands and any exposed skin thoroughly after handling Contaminated work clothing should not be allowed out of the workplace. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If skin irritation or rash occurs: Get medical advice/attention. Wash contaminated clothing before reuse. In case of fire: Use CO2, dry chemical, or foam Dispose of contents/ container to an approved waste disposal plant

Other References

Harmonized Tariff Code


  • A14774

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  • L04297

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  • L13174

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  • L19235

    4-Fluorophenylacetyl chloride, 97%
  • H63079

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