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2-Iodopyridine is a reagent used in the preparation of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors.
Damien Y. Duveau; Adam Yasgar; Yuhong Wang; Xin Hu; Jennifer Kouznetsova; Kyle R. Brimacombe; Ajit Jadhav; Anton Simeono; Craig J. Thomas; David J. Maloneyl. Structure-activity relationship studies and biological characterization of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors. Bioorganic & Medicinal Chemistry Letters. 2014, 24 (2), 401-409.
H- H. Tai; H. Cho, M. Tong; and Y. Ding. NAD+-Linked 15-Hydroxyprostaglandin Dehydrogenase: Structure and Biological Functions. Curr. Pharm. Des. 2006, 12 (8), 955 - 962.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant