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H63722 (R)-1-[alpha-(4-Chlorophenyl)benzyl]piperazine, 97%

CAS Number
300543-56-0
Synonyms
(-)-1-[(4-Chlorophenyl)phenylmethyl]piperazine

Stock No. Size Price ($) Quantity Availability
H63722-MD 250mg 26.80
H63722-03 1g 84.40
H63722-06 5g 385.00
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(R)-1-[alpha-(4-Chlorophenyl)benzyl]piperazine, 97%

MDL
MFCD11519277

Chemical Properties

Formula
C17H19ClN2
Formula Weight
286.8
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in chloroform, methanol, and dichloromethane. Slightly soluble in water.

Applications

(R)-1-[alpha-(4-Chlorophenyl)benzyl]piperazine intermediate in the production of (R)-Cetirizine.

Notes

Store in cool, dry place in tightly closed container. With adequate ventilation. Store away from oxidizing agent.

Literature References

Timothy A Lewis; Lynn Bayless; Joseph B Eckman; James L Ellis; Gurmit Grewal; Lyn Libertine; Jean Marie Nicolas; Ralph T Scannell; Bruce F Wels; Karen Wenberg; Donna M Wypij. 5-Lipoxygenase inhibitors with histamine H1 receptor antagonist activity. Bioorganic & Medicinal Chemistry Letters. 1985, 14(9), 2265-2268.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Harmonized Tariff Code
2933.59
TSCA
No

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