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300543-56-0 - (R)-1-[alpha-(4-Chlorophenyl)benzyl]piperazine, 97% - (-)-1-[(4-Chlorophenyl)phenylmethyl]piperazine - H63722 - Alfa Aesar

H63722 (R)-1-[alpha-(4-Chlorophenyl)benzyl]piperazine, 97%

CAS Number
300543-56-0
Synonyms
(-)-1-[(4-Chlorophenyl)phenylmethyl]piperazine

Size Price ($) Quantity Availability
250mg 25.80
1g 82.30
5g 343.00
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(R)-1-[alpha-(4-Chlorophenyl)benzyl]piperazine, 97%

MDL
MFCD11519277

Chemical Properties

Formula
C17H19ClN2
Formula Weight
286.8
Solubility
Soluble in chloroform, methanol, and dichloromethane. Slightly soluble in water.

Applications

(R)-1-[alpha-(4-Chlorophenyl)benzyl]piperazine intermediate in the production of (R)-Cetirizine.

Notes

Store in cool, dry place in tightly closed container. With adequate ventilation. Store away from oxidizing agent.

Literature References

Timothy A Lewis; Lynn Bayless; Joseph B Eckman; James L Ellis; Gurmit Grewal; Lyn Libertine; Jean Marie Nicolas; Ralph T Scannell; Bruce F Wels; Karen Wenberg; Donna M Wypij. 5-Lipoxygenase inhibitors with histamine H1 receptor antagonist activity. Bioorganic & Medicinal Chemistry Letters. 1985, 14(9), 2265-2268.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P312a-P321-P332+P313-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Specific treatment (see label). If skin irritation occurs: Get medical advice/attention. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2933.59
TSCA
No

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