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7306-68-5 - 6-Chloro-9-(2-tetrahydropyranyl)purine, 99% - H63779 - Alfa Aesar

H63779 6-Chloro-9-(2-tetrahydropyranyl)purine, 99%

CAS Number
7306-68-5
Synonyms

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6-Chloro-9-(2-tetrahydropyranyl)purine, 99%

MDL
MFCD00022821
EINECS
230-757-4

Chemical Properties

Formula
C10H11ClN4O
Formula Weight
238.68
Melting point
149-151°
Flash Point
213°(415°F)
Density
1.604
Refractive Index
1.7410

Applications

6-Chloro-9-(2-tetrahydropyranyl)purine is used to prepare 6-anilino-9-(2-tetrahydropyranyl)purine by reacting with bromobenzene in the presence of potassium amide as a reagent. Further, it serves as an intermediate in organic synthesis and pharmaceuticals.

Notes

Incompatible with oxidizing agents.

Literature References

Hocek, M.; Holý, A. Perfluoroalkylation of 6-Iodopurines by Trimethyl(perfluoroalkyl)silanes. Synthesis of 6-(Perfluoroalkyl)purine Bases, Nucleosides and Acyclic Nucleotide Analogues. Collect. Czech. Chem. Commun. 1999, 64 (2), 229-241.

Taddei, D.; Kilian, P.; Slawin, A. M. Z.; Woollins, J. D. Synthesis and full characterisation of 6-chloro-2-iodopurine, a template for the functionalisation of purines. Org. Biomol. Chem. 2004, 2 (5), 665-670.

GHS Hazard and Precautionary Statements

Precautionary Statements: P260-P201-P280-P304+P340-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2934.99
TSCA
No

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