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18822-58-7 - O-tert-Butyl-L-serine, 98% - H-Ser(tBu)-OH - (S)-2-Amino-3-(tert-butoxy)propionic acid - H63812 - Alfa Aesar

H63812 O-tert-Butyl-L-serine, 98%

CAS Number
18822-58-7
Synonyms
H-Ser(tBu)-OH
(S)-2-Amino-3-(tert-butoxy)propionic acid

Size Price ($) Quantity Availability
1g 36.70
5g 147.00
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O-tert-Butyl-L-serine, 98%

MDL
MFCD00066088

Chemical Properties

Formula
C7H15NO3
Formula Weight
161.2
Melting point
220° dec
Solubility
Soluble in water.

Applications

O-tert-Butyl-L-serine tert-butyl ester hydrochloride is a protected L-serine used in peptide synthesis, e.g. synthesis of glycopeptides and lipopeptides and preparation of amino-phospholipids. O-tert-Butyl-L-serine (Ser(TBU-OH), a serine hydroxyl protected amino acid, is used in SPPS such as the synthesis of tailed cyclic RGD peptides to prevent glutarimide formation.

Notes

Light Sensitive.Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, light, heat.

Literature References

V Cerovský et. al. A convenient incorporation of conformationally constrained 5,5-dimethylproline into the ribonuclease A 89-124 sequence by condensation of synthetic peptide fragments. . Journal of Peptide Research. 2003, 61(3), 140-151 .

Nancy M. Tooney,; Gerald D. Fasman. Synthesis of poly-O-tert-butyl-L-serine and poly-L-serine. Biopolymers. 1968 , 6 (1), 81-96.

Other References

Beilstein
2500118
Harmonized Tariff Code
2922.50
TSCA
No

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