3-(3-Pyridyl)-L-alanine is a antimycobacterial cyclodepsipeptide. PyrA is used to activate other aromatic acids.
Tingting Huang,; Yemin Wang ,; Yin,; Yanhua Du,; Meifeng Tao,; Jing Xu,; Wenqing Chen,; Shuangjun Lin,; Zixin Deng. Identification and Characterization of the Pyridomycin Biosynthetic Gene Cluster of Streptomyces pyridomyceticus NRRL B-2517title . The Journal of Biological Chemistry, 2011, 286, 20648-20657.
Hu, Jialiang; Yan, Ming; Pu, Chunyan; Wang, Jingjing; E. Van den Steen, Philippe; Opdenakker, Ghislain; Xu, Hanmei. Chemically Synthesized Matrix Metalloproteinase and Angiogenesis-inhibiting Peptides as Anticancer Agents. / Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry - Anti-Cancer Agents. 2013, 14(3), 483-494.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.