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(R)-N-methyl-2-methylbenzylamine is resistant to displacement by the aqueous extractants.
A. John Blacker,; Stuart Brown,; Blandine Clique,; Brian Gourlay,; Catherine E. Headley,; Stephen Ingham,; Dougal Ritson,; Thomas Screen,; Matthew J. Stirling,; David Taylor,; Gary Thompson. A Low-Waste Process To Sertraline By Diastereomeric Crystal Resolution and Waste Isomer Racemisation. Org. Process Res. Dev. 2009, 13 (6), 1370-1378o.
Hazard Statements: H314-H318
Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statements: P260u-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.