Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

H64026 4-Bromo-2-methoxypyridine, 98%

CAS Number
100367-39-3
Synonyms

Stock No. Size Price ($) Quantity Availability
H64026-03 1g 38.40
H64026-06 5g 140.00
Add to Cart Bulk/Specialty Print Quote View Item

4-Bromo-2-methoxypyridine, 98%

MDL
MFCD08277268

Chemical Properties

Formula
C6H6BrNO
Formula Weight
188.02
Melting point
25-26°
Boiling Point
87°/15mm
Storage & Sensitivity
Keep Cold.
Solubility
Slightly soluble in water.

Applications

4-Bromo-2-methoxypyridine used in the synhesis of Imidazo [1, 2-a] pyrimidines. Suzuki coupling between 4-methoxyphenylboronic acid and 4-bromo-2-methoxypyridine affords 1, 5-disubstituted pyridones. Starting material used in a synthesis of crown-ester-bipyridines and viologens via sodium or nickel reductive coupling, side chain oxidation and esterification.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, heat.

Literature References

F. Trecourt, M. Mallet, F. Marsais, G. Queguiner.Catalyzed metalation applied to 2-methoxypyridine . J. Org. Chem. 1988, 53 (7), 1367-1371.

Wesley P. Blackaby,; John R. Atack,; Frances Bromidge,; José L. Castro,; Simon C. Goodacre,; David J. Hallett. Imidazo[1,2-a]pyrimidines as functionally selective GABAA ligands. Bioorganic & Medicinal Chemistry Letters. 2005, 16 (5), 1175-1179.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
115199
Harmonized Tariff Code
2933.39
TSCA
No

Recommended

  • H64562

    2-Fluoro-3-nitrobenzotrifluoride, 98%
  • 43290

    Cobalt wire, 2.0mm (0.08in) dia, 99.95% (metals basis)
  • L11005

    2-Bromoethyl phenyl sulfide, 97%
  • B22928

    trans-1,2-Diaminocyclohexane-N,N,N',N'-tetraacetic acid monohydrate, 98%
  • 31558

    Al-23 Tube (both ends open);OD (mm), 7;ID (mm), 4

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware