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Reatant in the synthesis of N-fused tricyclic indoles, dimethyamine, benzofuran.
R. Graham Robinet,; Alex J. Freemerman,; Michael A. Skinner,; Lisa Shewchuk,; Karen Lackey. The discovery of substituted 4-(3-hydroxyanilino)-quinolines as potent RET kinase inhibitors. Bioorganic & Medicinal Chemistry Letters. 2007, 17 (21), 5886-5893.
Baudouin Gerard,; Maurice D. LeeIV,; Sivaraman Dandapani,; Jeremy R. Duvall, ;Mark E. Fitzgerald,; Sarathy Kesavan,; Jason T. Lowe,; Jean-Charles Marié,; Bhaumik A. Pandya,; Byung-Chul Suh. Synthesis of Stereochemically and Skeletally Diverse Fused Ring Systems from Functionalized C-Glycosides. J. Org. Chem. 2013, 78 (11), 5160-5171.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant