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22282-72-0 - 2-Hydroxypyridine-4-carboxylic acid, 98% - 2-Hydroxyisonicotinic acid - H64241 - Alfa Aesar

H64241 2-Hydroxypyridine-4-carboxylic acid, 98%

CAS Number
22282-72-0
Synonyms
2-Hydroxyisonicotinic acid

Size Price ($) Quantity Availability
5g 35.30
25g 141.00
100g 564.00
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2-Hydroxypyridine-4-carboxylic acid, 98%

MDL
MFCD01318566

Chemical Properties

Formula
C6H5NO3
Formula Weight
139.11

Applications

Used in the synthesis of selective inhibitors of neuropeptide Y Y5 inhibiting food intake. Also used in the optimization of p-subsite residues of HIV protease inhibitors.

Notes

Store in cool, dry place in tightly closed container. With adequate ventilation. Store away from oxidizing agent.

Literature References

Ando, M. et al. Discovery of pyridone-containing imidazolines as potent and selective inhibitors of neuropeptide Y Y5 receptor. Bioorganic & Medicinal Chemistry. 2009 17(16), 6106-6122.

Ashraf Brik; Ying-Chuan Lin; John Elder; Chi-Huey Wong. A quick diversity-oriented amide-forming reaction to optimize P-subsite residues of HIV protease inhibitors. Chem. Biol. 2002 9(8), 891-896.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
115859
Harmonized Tariff Code
2933.39
TSCA
No

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