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H64241 2-Hydroxypyridine-4-carboxylic acid, 98%

CAS Number
22282-72-0
Synonyms
2-Hydroxyisonicotinic acid

Stock No. Size Price ($) Quantity Availability
H64241-06 5g 36.50
H64241-14 25g 144.00
H64241-22 100g 576.00
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2-Hydroxypyridine-4-carboxylic acid, 98%

MDL
MFCD01318566

Chemical Properties

Formula
C6H5NO3
Formula Weight
139.11
Storage & Sensitivity
Ambient temperatures.

Applications

Used in the synthesis of selective inhibitors of neuropeptide Y Y5 inhibiting food intake. Also used in the optimization of p-subsite residues of HIV protease inhibitors.

Notes

Store in cool, dry place in tightly closed container. With adequate ventilation. Store away from oxidizing agent.

Literature References

Ando, M. et al. Discovery of pyridone-containing imidazolines as potent and selective inhibitors of neuropeptide Y Y5 receptor. Bioorganic & Medicinal Chemistry. 2009 17(16), 6106-6122.

Ashraf Brik; Ying-Chuan Lin; John Elder; Chi-Huey Wong. A quick diversity-oriented amide-forming reaction to optimize P-subsite residues of HIV protease inhibitors. Chem. Biol. 2002 9(8), 891-896.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
115859
Harmonized Tariff Code
2933.39
TSCA
No

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