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5597-50-2 - Methyl 3-(4-hydroxyphenyl)propionate, 98% - 3-(4-Hydroxyphenyl)propionic acid methyl ester - H64255 - Alfa Aesar

H64255 Methyl 3-(4-hydroxyphenyl)propionate, 98%

CAS Number
5597-50-2
Synonyms
3-(4-Hydroxyphenyl)propionic acid methyl ester

Size Price ($) Quantity Availability
25g 48.20
100g 191.00
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Methyl 3-(4-hydroxyphenyl)propionate, 98%

MDL
MFCD00071577

Chemical Properties

Formula
C10H12O3
Formula Weight
180.20
Melting point
39-41° lit.
Boiling Point
108°/11mm
Flash Point
>113°(235°F)
Solubility
Soluble in chloroform and methanol.

Applications

Useful synthetic intermediate. It can be used to prepare potent and orally available G protein-coupled receptor 40 agonists as potential antidiabetic agents. May be used in the enzymatic coupling of saccharides to protein.

Notes

Store in cool, dry place in tightly closed container. With adequate ventilation. Store away from oxidizing agent.

Literature References

Ruud ter Haar et. al. Proof of principle for the synthesis of hydroxy-aryl esters of glycosidic polyols and non-reducing oligosaccharides with subsequent enzymatic coupling to a tyrosine-containing tripeptide. Carbohydrate Research. 2011 346(8), 1005-1012.

Hossain A K M Zakir; Guntur V Subbarao; Stuart J Pearse; Subramaniam Gopalakrishnan; Osamu Ito; Takayuki Ishikawa; Naoyoshi Kawano; Kazuhiko Nakahara; Tadashi Yoshihashi; Hiroshi Ono; Mitsuru Yoshida. Detection, isolation and characterization of a root-exuded compound, methyl 3-(4-hydroxyphenyl) propionate, responsible for biological nitrification inhibition by sorghum (Sorghum bicolor). New Phytologist.2008 180(2), 442-451.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
2211073
Harmonized Tariff Code
2918.29
TSCA
No

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