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1439-10-7 - 4-Amino-5-bromopyrimidine, 98% - 5-Bromo-4-pyrimidinylamine - H64335 - Alfa Aesar

H64335 4-Amino-5-bromopyrimidine, 98%

CAS Number
1439-10-7
Synonyms
5-Bromo-4-pyrimidinylamine

Size Price ($) Quantity Availability
250mg 36.00
1g 108.00
5g 431.00
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4-Amino-5-bromopyrimidine, 98%

MDL
MFCD00233962

Chemical Properties

Formula
C4H4BrN3
Formula Weight
174.00
Melting point
207-211°
Solubility
Slightly soluble in water.

Applications

It is an inhibitor of thymidine phosphorylase, an enzyme known to be over-expressed in several tumor types and to play a role in metastasis.

Notes

Store in cool, dry place in tightly closed container. With adequate ventilation. Store away from oxidizing agent.

Literature References

Thomas J. Kress; and Larry L. Moore. Studies on the bromination of pyrimidine. A facile synthesis of 5-bromopyrimidine. Journal of Heterocyclic Chemistry.198910 (2), 153-157.

E. Kalatzis. Kinetics of the hydrolytic deamination of N-heteroaromatic amines in aqueous alkaline solutions. J. Chem. Soc. B.1969 (0), 96-104.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P301+P312a-P321-P332+P313-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF SWALLOWED: Specific treatment (see label). If skin irritation occurs: Get medical advice/attention. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
112648
Harmonized Tariff Code
2933.59
TSCA
No

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