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H64335 4-Amino-5-bromopyrimidine, 98%

CAS Number
1439-10-7
Synonyms
5-Bromo-4-pyrimidinylamine

Stock No. Size Price ($) Quantity Availability
H64335-MD 250mg 37.20
H64335-03 1g 111.00
H64335-06 5g 440.00
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4-Amino-5-bromopyrimidine, 98%

MDL
MFCD00233962

Chemical Properties

Formula
C4H4BrN3
Formula Weight
174.00
Melting point
207-211°
Storage & Sensitivity
Ambient temperatures.
Solubility
Slightly soluble in water.

Applications

It is an inhibitor of thymidine phosphorylase, an enzyme known to be over-expressed in several tumor types and to play a role in metastasis.

Notes

Store in cool, dry place in tightly closed container. With adequate ventilation. Store away from oxidizing agent.

Literature References

Thomas J. Kress; and Larry L. Moore. Studies on the bromination of pyrimidine. A facile synthesis of 5-bromopyrimidine. Journal of Heterocyclic Chemistry.198910 (2), 153-157.

E. Kalatzis. Kinetics of the hydrolytic deamination of N-heteroaromatic amines in aqueous alkaline solutions. J. Chem. Soc. B.1969 (0), 96-104.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Rinse mouth. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
112648
Harmonized Tariff Code
2933.59
TSCA
No

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