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H64339 5-Chloro-2-iodopyridine, 98%

CAS Number
244221-57-6
Synonyms

Stock No. Size Price ($) Quantity Availability
H64339-03 1g 64.90
H64339-06 5g 295.00
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5-Chloro-2-iodopyridine, 98%

MDL
MFCD07368864

Chemical Properties

Formula
C5H3ClIN
Formula Weight
239.44
Storage & Sensitivity
Keep Cold. Light Sensitive.
Solubility
Slightly soluble in water.

Applications

It is applied in an efficient preparation of indolizines through a tandem palladium-catalyzed cross-coupling reaction and cycloisomerization and also in the synthesis, and structure-activity relationships of 2-aminoquinazoline derivatives as a novel class of metabotropic glutamate receptor 5 negative allosteric modulators.

Notes

Light sensitive. Store away from heat, light and oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Protect from exposure to light. Keep it refrigerated.

Literature References

Manfred Schlosser, et al. Silyl-Mediated Halogen/Halogen Displacement in Pyridines and Other Heterocycles.Eur. J. Org. Chem.,2002,244181-4184.

Hyunseok Kim, et al. An efficient preparation of indolizines through a tandem palladium-catalyzed cross-coupling reaction and cycloisomerization.Chem. Commun.,2010,46(34), 6341-6343.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Rinse mouth. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
9321405
Harmonized Tariff Code
2933.39
TSCA
No

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