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33630-99-8 - 3-Amino-2-hydroxypyridine, 98% - 3-Amino-2-pyridinol - H64480 - Alfa Aesar

H64480 3-Amino-2-hydroxypyridine, 98%

CAS Number
33630-99-8
Synonyms
3-Amino-2-pyridinol

Size Price ($) Quantity Availability
250mg 24.30
1g 39.40
5g 292.00
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3-Amino-2-hydroxypyridine, 98%

MDL
MFCD03411556

Chemical Properties

Formula
C5H6N2O
Formula Weight
110.12
Solubility
Slightly soluble in water.

Applications

It is used as pharmaceutical intermediate. It is involved in synthesis of functionalized pyrido[4,3-b][1,4]oxazine and imidazo[1,2-a]pyridine derivatives. The use of ethyl 2-chloro-3-oxopropanoate with 2-amino-3-hydroxypyridine or 3-amino-4-hydroxypyridine led, respectively, to imidazo[1,2-a]pyridine derivatives or ethyl pyrido[4,3-b][1,4] oxazine-2-carboxylate.

Notes

Store in cool dry place. Keep container tightly closed. Incompatible with oxidizing agents.

Literature References

Axelle Arrault.; Frédérique Touzeau.; Gérald Guillaumet.; Jean-Michel Léger.; Christian Jarry.; Jean-Yves Méroura. Synthesis of functionalised pyrido[4,3-b][1,4]oxazine and imidazo[1,2-a]pyridine derivatives.Tetrahedron. 2002, 58 (40), 8145-8152 .

Margaret Y. Chu-Moyer.; Richard Berger. Preparation of the Four Regioisomeric 2-(Methylthio)oxazolopyridines: Useful Synthons for Elaboration to 2-(Amino substituted)oxazolopyridines.J. Org. Chem. 1995, 60 (17),5721-5725 .

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
109849
Harmonized Tariff Code
2933.39
TSCA
No

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