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64622-16-8 - 2-Bromo-6-chlorobenzaldehyde, 98% - H64605 - Alfa Aesar

H64605 2-Bromo-6-chlorobenzaldehyde, 98%

CAS Number
64622-16-8
Synonyms

Size Price ($) Quantity Availability
250mg 38.80
1g 104.00
5g 388.00
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2-Bromo-6-chlorobenzaldehyde, 98%

MDL
MFCD00266792

Chemical Properties

Formula
C7H4BrClO
Formula Weight
219.46
Melting point
81-86°
Solubility
Slightly soluble in water. 

Applications

2-Bromo-6-chlorobenzaldehyde plays an important role as a linker, which provides higher selectivity and reactivity in the Buchwald C-N bond forming reaction in order to prepare Bruton's tyrosine kinase inhibitor.

Notes

Store in a cool place. Air sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.

Literature References

Sahn, J. J.; Su, J. Y.; Martin, S. F. Facile and unified approach to skeletally diverse, privileged scaffolds. 2011, 13 (10), 2590-2593.

Donald, J. R.; Granger, B. A.; Hardy, S.; Sahn, J. J.; Martin, S. F. Applications of Multicomponent Assembly Processes To the Facial Synthesis of Diversely Functionalized Nitrogen Heterocycles. 2012, 84 (2), 1089.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
2613087
Harmonized Tariff Code
2913.00
TSCA
No

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