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8-Bromo-1-octene has been used in preparation of polymerizable ligand, required for the synthesis of quantum dot-labeled polymer beads. Grignard reagent derived from 8-bromo-1-octene has been used in the synthesis of (2S,3S,5R)-5-[(1R)-1-hydroxy-9-decenyl]-2-pentyltetrahydro-3-furanol. It has been used as building block in natural product synthesis. Also used for the synthesis of more complex pharmaceutical compounds, such as Dithienogermole (DTG) derivatives with varying alkyl chain lengths and pendant functionalities.
Paul O'Brien; Siobhan S Cummins; Dan Darcy; Angela Dearden; Ombretta Masala; Nigel L Pickett; Steve Ryley; Andrew J Sutherland. Quantum dot-labelled polymer beads by suspension polymerisation. Chemical Communications.2003 202532-2533.
Christophe Dubost; Istvan E Markó; Thomas Ryckmans. A concise total synthesis of the lichen macrolide (+)-aspicilin. Organic Letters.2006 8(22), 5137-5140.
Hazard Statements: H227-H315-H319-H335
Combustible liquid. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P210u-P261-P280a-P305+P351+P338-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.