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80194-69-0 - 5-(Trifluoromethyl)pyridine-2-carboxylic acid, 95% - 5-(Trifluoromethyl)picolinic acid - H64937 - Alfa Aesar

H64937 5-(Trifluoromethyl)pyridine-2-carboxylic acid, 95%

CAS Number
80194-69-0
Synonyms
5-(Trifluoromethyl)picolinic acid

Size Price ($) Quantity Availability
1g 28.40
5g 113.00
25g 469.00
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5-(Trifluoromethyl)pyridine-2-carboxylic acid, 95%

MDL
MFCD04113632

Chemical Properties

Formula
C7H4F3NO2
Formula Weight
191.11
Melting point
133-137°
Solubility
Slightly soluble in water.

Applications

5-(Trifluoromethyl)pyridine-2-carboxylic acid is an intermediate used in the synthesis of β-secretase (BACE) inhibitors.

Notes

Store in cool, dry place in tightly closed container. With adequate ventilation. Store away from oxidizing agent.

Literature References

Roger Crettaz; Jérôme Waser; and Yves Bessard. Synthetic Process Development and Scale Up of Palladium-Catalyzed Alkoxycarbonylation of Chloropyridines. Org. Proc. Res. Dev.2001 5(6), 572-574.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2933.39
TSCA
No

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