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H66006 (R)-(+)-4-Hydroxy-2-pyrrolidinone, 97+%

CAS Number
22677-21-0
Synonyms
(R)-beta-Hydroxy-gamma-butyrolactam

Stock No. Size Price ($) Quantity Availability
H66006-MD 250mg 36.30
H66006-03 1g 113.00
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(R)-(+)-4-Hydroxy-2-pyrrolidinone, 97+%

MDL
MFCD00273364

Chemical Properties

Formula
C4H7NO2
Formula Weight
101.10
Melting point
155-160°
Storage & Sensitivity
Ambient temperatures.
Solubility
Slightly soluble in water.

Applications

(R)-(+)-4-Hydroxy-2-pyrrolidinone intermediate in the preparation of Oxiracetam. Also used as enantiomeric intermediate for the asymmetric single isomeric drugs including antitumor, anesthetic, antipasmodic, anti-inflammatory or anti-HIV activity products.

Notes

Store in cool, dry place in tightly closed container. With adequate ventilation. Store away from oxidizing agent.

Literature References

Christopher S. P.; McErlean; and Christopher J. Moody. First Synthesis of N-(3-Carboxylpropyl)-5-amino-2-hydroxy-3- tridecyl-1,4-benzoquinone, an Unusual Quinone Isolated from Embelia ribes. J. Org. Chem.2007 72(26), 10298-10301.

Dilip K. Kondepudi; Rebecca J. Kaufman; Nolini Singh. Chiral Symmetry Breaking in Sodium Chlorate Crystallizaton. J. Org. Chem.1990 250 975-976 .

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
1524193
Harmonized Tariff Code
2933.99
TSCA
No

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