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286961-14-6 - N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester, 95% - H66193 - Alfa Aesar

H66193 N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester, 95%

CAS Number
286961-14-6
Synonyms

Size Price ($) Quantity Availability
1g 54.90
5g 206.00
25g 823.00
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N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester, 95%

MDL
MFCD03840345

Chemical Properties

Formula
C16H30BNO5
Formula Weight
327.23
Solubility
Soluble in most organic solvents. Insoluble in water.

Applications

Reagent used for suzuki-Miyaura cross-coupling using palladium phosphine catalyst, palladium-catalyzed ligand-controlled regioselective Suzuki coupling, wrenchnolol derivative optimized for gene activation in cells. Also used in Preparation of several enzymatic inhibitors and receptor ligands, orally active anaplastic lymphoma kinase inhibitors and oxazolecarboxamides as diacylglycerol acyltransferase-1 inhibitors for treatment of obesity and diabetes.

Notes

Store in cool, dry place in tightly closed container. With adequate ventilation. Store away from oxidizing agent.

Literature References

Tang, Q; Gianatassio, R. Synthesis of 1,5-disubstituted tetrazoles via Suzuki-Miyaura cross-coupling of 5-chloro-1-phenyltetrazole. Tetrahedron Lett.2010513473-3476.

Neil A Strotman; Harry R Chobanian; Jiafang He; Yan Guo; Peter G Dormer; Christina M Jones; Janelle E Steves. Catalyst-controlled regioselective Suzuki couplings at both positions of dihaloimidazoles, dihalooxazoles, and dihalothiazoles. Journal of Organic Chemistry.201075(5), 1733-1739.

Other References

Harmonized Tariff Code
2934.99
TSCA
No

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