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N-Isopropylacrylamide is used to produce poly(N-isopropylacrylamide) (pNIPA, pNIPAAm, pNIPAA or pNIPAm) thermo sensitive polymer- or copolymer-based hydrogels. Polymers that contain NIPAM shrink dramatically above 33°C. Monomer used in the preparation of thermally sensitive, water-swellable hydrogels.
Firdaus Yhaya; Sandra Binauld; Yoseop Kim; Martina H Stenzel. Shell cross-linking of cyclodextrin-based micelles via supramolecular chemistry for the delivery of drugs. Macromolecular Rapid Communications.201233(21), 1868-1874.
R Yoshida. [Controlled release using temperature-responsive poly(N-isopropylacrylamide) gel]. Japanese journal of clinical medicine.199856(3), 670-674.
Hazard Statements: H302-H319
Harmful if swallowed. Causes serious eye irritation.
Precautionary Statements: P264b-P270-P280i-P301+P312-P305+P351+P338-P330-P337+P313-P501c
Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Wear eye/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Rinse mouth. If eye irritation persists: Get medical advice/attention. Dispose of contents/ container to an approved waste disposal plant