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148-79-8 - Thiabendazole, 98+% - 2-(4-Thiazolyl)benzimidazole - J60009 - Alfa Aesar

J60009 Thiabendazole, 98+%

CAS Number
148-79-8
Synonyms
2-(4-Thiazolyl)benzimidazole

Size Price ($) Quantity Availability
10g 23.60
100g 108.00
500g 418.00
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Thiabendazole, 98+%

MDL
MFCD00005587
EINECS
205-725-8

Chemical Properties

Formula
C10H7N3S
Formula Weight
201.25
Form
Powder
Melting point
304-305°
Solubility
Soluble in methanol and dimethyl sulfoxide.

Applications

Thiabendazole, a metal chelator and helminth-specific fumarate reductase inhibitor, is used primarily as an anthelmintic to control infections by helminth organisms. It is also used to control mold and fungal growth in plants. Also used to treat parasitic infections in humans. It is used clinically to treat threadworm, cutaneous larva migrans, visceral larva migrans, and trichinosis.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.

Literature References

Roslyn S Thelingwani; Simbarashe P Zvada; Hugues Dolgos; Anna-Lena B Ungell; Collen M Masimirembwa. In vitro and in silico identification and characterization of thiabendazole as a mechanism-based inhibitor of CYP1A2 and simulation of possible pharmacokinetic drug-drug interactions. Drug Metabolism and Disposition, 2009, 37(6), 1286-1294.

Craig Knox et. al. DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Research, 2012, 39(3), D1035-D1041.

GHS Hazard and Precautionary Statements

Hazard Statements: H400-H410

Very toxic to aquatic life. Very toxic to aquatic life with long lasting effects.

Precautionary Statements: P273-P391-P501a

Avoid release to the environment. Collect spillage. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,9289
Beilstein
611403
Hazard Class
9
Packing Group
III
Harmonized Tariff Code
2934.10
TSCA
Yes
RTECS
DE0700000

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