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Thiabendazole, a metal chelator and helminth-specific fumarate reductase inhibitor, is used primarily as an anthelmintic to control infections by helminth organisms. It is also used to control mold and fungal growth in plants. Also used to treat parasitic infections in humans. It is used clinically to treat threadworm, cutaneous larva migrans, visceral larva migrans, and trichinosis.
Roslyn S Thelingwani; Simbarashe P Zvada; Hugues Dolgos; Anna-Lena B Ungell; Collen M Masimirembwa. In vitro and in silico identification and characterization of thiabendazole as a mechanism-based inhibitor of CYP1A2 and simulation of possible pharmacokinetic drug-drug interactions. Drug Metabolism and Disposition, 2009, 37(6), 1286-1294.
Craig Knox et. al. DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Research, 2012, 39(3), D1035-D1041.