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J60033 Methylguanidine hydrochloride, 98%

CAS Number
22661-87-6
Synonyms
TMG hydrochloride

Stock No. Size Price ($) Quantity Availability
J60033-06 5g 75.50
J60033-14 25g 212.00
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Methylguanidine hydrochloride, 98%

MDL
MFCD00012576
EINECS
245-147-3

Chemical Properties

Formula
C2H7N3•HCl
Formula Weight
109.56
Form
Crystalline Powder
Storage & Sensitivity
Store at -20°C. Hygroscopic.
Solubility
Soluble in water (50 mg/ml - clear, colorless to light yellow solution).

Applications

Methylguanidine hydrochloride can be used in the synthesis of biaryl derivatives which were evaluated as BACE1 inhibitors.

Notes

Hygroscopic, store away form water/moisture. Store in freezer -20°C. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent and reducing agent.

Literature References

Tadashi. Inagami; Sheldon S. York. Effect of alkyl guanidines and alkyl amines on trypsin catalysis. Biochemistry, 1968, 7(11), 4045-4052.

GuÈluÈzar Yildiz; A. Tuncay DemiryuÈrek; Inci Sahin-Erdemli; and Ilker Kanzik. Comparison of antioxidant activities of aminoguanidine, methylguanidine and guanidine by luminol-enhanced chemiluminescence. British Journal of Pharmacology, 1998 124, 905-910.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2925.29
TSCA
No
RTECS
MF3990000

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