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N-Lauroylsarcosine is used for solubilization and separation of membrane proteins and glycoprotein's; reported to inhibit hexokinase. It is useful in concentrated salt solutions used in the cell lysis step during RNA purification (helps avoid excessive foaming). It has been used to indicate paramagnetic anisotropy sign change in micelle mesophage. Inhibits bacterial flora of human saliva/gut at 0.25% as well as acting as a fungi static agent in aqueous dispersion (1%).
P Gariglio; J Buss; M H Green. Sarkosyl activation of RNA polymerase activity in mitotic mouse cells. FEBS Letters, 1974, 44(3), 330-333.
R J MacDonald; G H Swift; A E Przybyla; J M Chirgwin. Isolation of RNA using guanidinium salts. Methods in Enzymology, 1987 152 219-227.
Hazard Statements: H330-H315-H318
Fatal if inhaled. Causes skin irritation. Causes serious eye damage.
Precautionary Statements: P260-P201-P280g-P304+P340-P405-P501a
Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.