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137-16-6 - N-Lauroylsarcosine sodium salt, 95% - N-Dodecanoyl-N-methylglycine sodium salt - Sarkosyl NL - J60040 - Alfa Aesar

J60040 N-Lauroylsarcosine sodium salt, 95%

CAS Number
137-16-6
Synonyms
N-Dodecanoyl-N-methylglycine sodium salt
Sarkosyl NL

Size Price ($) Quantity Availability
10g 55.62
50g 199.20
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N-Lauroylsarcosine sodium salt, 95%

MDL
MFCD00042728
EINECS
205-281-5

Chemical Properties

Formula
C15H29NNaO3
Formula Weight
293.39
Form
Crystalline powder
Melting point
44-47°
Sensitivity
Hygroscopic
Solubility
Soluble in water (293 g/L).

Applications

N-Lauroylsarcosine is used for solubilization and separation of membrane proteins and glycoprotein's; reported to inhibit hexokinase. It is useful in concentrated salt solutions used in the cell lysis step during RNA purification (helps avoid excessive foaming). It has been used to indicate paramagnetic anisotropy sign change in micelle mesophage. Inhibits bacterial flora of human saliva/gut at 0.25% as well as acting as a fungi static agent in aqueous dispersion (1%).

Notes

Hygroscopic, store away form water/moisture. Store in cool. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent and reducing agent.

Literature References

P Gariglio; J Buss; M H Green. Sarkosyl activation of RNA polymerase activity in mitotic mouse cells. FEBS Letters, 1974, 44(3), 330-333.

R J MacDonald; G H Swift; A E Przybyla; J M Chirgwin. Isolation of RNA using guanidinium salts. Methods in Enzymology, 1987 152 219-227.

GHS Hazard and Precautionary Statements

Hazard Statements: H330-H315-H318

Fatal if inhaled. Causes skin irritation. Causes serious eye damage.

Precautionary Statements: P260-P284-P280-P304+P340-P305+P351+P338-P320-P310-P362-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Wear respiratory protection. Wear protective gloves/protective clothing/eye protection/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Specific treatment is urgent (see label). Immediately call a POISON CENTER or doctor/physician. Take off contaminated clothing and wash before reuse. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,4368
Beilstein
5322974
Hazard Class
6.1
Packing Group
II
Harmonized Tariff Code
2924.19
TSCA
Yes
RTECS
MC0598960

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