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4781-83-3 - 2-Iminothiolane hydrochloride - 2-Thiolanimine hydrochloride - Traut's reagent - J60131 - Alfa Aesar

J60131 2-Iminothiolane hydrochloride

CAS Number
4781-83-3
Synonyms
2-Thiolanimine hydrochloride
Traut's reagent

Size Price ($) Quantity Availability
250mg 143.00
1g 189.00
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2-Iminothiolane hydrochloride

MDL
MFCD00039013

Chemical Properties

Formula
C4H7NS•HCl
Formula Weight
137.63
Form
Powder
Melting point
190-195°
Solubility
Freely soluble in water

Applications

2-Iminothiolane hydrochloride is predominantly used as an amine reactive at pH 7-10 and is also an effective thiolation reagent for polysaccharides. It is also used as a RNA-protein crosslinking reagent as well as useful in cross-linking proteins..

Notes

Protect from moisture. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C. Keep away fom strong oxidizing agents.

Literature References

A Bernkop-Schnürch.; M Hornof.; T Zoidl. Thiolated polymers—thiomers: synthesis and in vitro evaluation of chitosan-2-iminothiolane conjugates. International Journal of Pharmaceutics. 2003, 260,(2), 229-237.

R Jue.; JM Lambert.; LR Pierce.; RR Traut. Addition of sulfhydryl groups of Escherichia coli ribosomes by protein modification with 2-iminothiolane (methyl 4-mercaptobutyrimidate). Biochemistry. 1978, 17,(25), 5399-5406.

Other References

Beilstein
3620079
Harmonized Tariff Code
2934.99
TSCA
No

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