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Loratadine, is used as a peripheral histamine H1 receptor agonist. It is also used as an orally active antiallergic agent. It is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuff.
Barnett et al. Evaluation of the CNS properties of SCH 29851, a potential non-sedating antihistamine. Agents Actions. 1984, 14,(5-6), 590-7.
Kreutner et al. Antiallergic activity of loratidine, a non-sedating antihistamine. Allergy. 1987, 42,(1), 57-63.