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Sodium orthovanadate, is used as an inhibitor of several phosphatases and kinases such as protein tyrosine phosphatases (PTPs), alkaline phosphatase (ALP), and ATPase. It also acts as an inhibitor of adenosine kinase (AK) and phosphofructokinase (PFK). It also suppresses p53-mediated apoptosis by transcription-dependent and -independent pathways.
Ai et al. Inhibition of small-intestinal sugar absorption mediated by sodium orthovanadate Na3VO4 in rats and its mechanisms. World J.Gastroenterol. 2004, 15,(24), 3612-5.
Matsumoto et al. Sodium orthovanadate enhances proliferation of progenitor cells in the adult rat subventricular zone after focal cerebral ischemia. J.Pharmacol.Exp.Ther. 2006, 318,(3), 982-91.
Hazard Statements: H333
May be harmful if inhaled.
Precautionary Statements: P304+P312a