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Theophylline has been used to study its effects on rat gene expression in the ubiquitin-proteasome pathway that regulates spermatogenesis and epididymal sperm quality. Theophylline has also been used as an internal standard for the measurement of plasma paracetamol levels in humans.
Mark W Tengowski; Dongyan Feng; Miriam Sutovsky; Peter Sutovsky. Differential expression of genes encoding constitutive and inducible 20S proteasomal core subunits in the testis and epididymis of theophylline- or 1,3-dinitrobenzene-exposed rats. Biology of Reproduction, 2007, 76(1), 149-163.
F J Sevilla-Tirado et. al.Bioavailability of two new formulations of paracetamol, compared with three marketed formulations, in healthy volunteers.. Methods and Findings in Experimental and Clinical Pharmacology, 2003,25,(7), 531-535.
Hazard Statements: H301
Toxic if swallowed.
Precautionary Statements: P264-P270-P301+P310a-P321-P405-P501a
Wash thoroughly after handling. Do not eat, drink or smoke when using this product. IF SWALLOWED: Immediately call a POISON CENTER/doctor Specific treatment (see label). Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.