Oligomycin A, is used as inhibitor of mitochondrial ATP synthase and uncoupler of oxidative phosphorylation. Antibiotic, exhibits anti-tumor activity.
Salomon et al. Apoptolidin, a selective cytotoxic agent, is an inhibitor of F0F1-ATPase. Chem.Biol. 2001, 8,(1), 71-80.
HA Lardy.; P Witonsky.; D Johnson. Antibiotics as Tools for Metabolic Studies. IV. Comparative Effectiveness of Oligomycins A, B, C, and Rutamycin as Inhibitors of Phosphoryl Transfer Reactions in Mitochondria. Biochemistry. 1965, 4,(3), 552-554.
Hazard Statements: H302
Harmful if swallowed.
Precautionary Statements: P260-P201-P280-P304+P340-P405-P501a
Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.