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298-83-9 - Nitro Blue Tetrazolium chloride, 99% - Nitro BT - Nitrotetrazolium Blue chloride - J60230 - Alfa Aesar

J60230 Nitro Blue Tetrazolium chloride, 99%

CAS Number
298-83-9
Synonyms
Nitro BT
Nitrotetrazolium Blue chloride

Size Price ($) Quantity Availability
1g 57.89
5g 277.07
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Nitro Blue Tetrazolium chloride, 99%

MDL
MFCD00012159
EINECS
206-067-4

Chemical Properties

Formula
C40H30Cl2N10O6
Formula Weight
817.65
Form
Crystalline powder
Melting point
ca 190° dec.
Solubility
Soluble in water, ethanol and methanol.

Applications

Intense blue dye used in histochemistry determinations.Nitro Blue Tetrazolium chloride is used to confirm diagnosis of chronic granulomatous disease. It is a microscopic stain, which is used to detect dehydrogenases and alkaline phosphatase. It acts as an NADPH-diaphorase substrate that competitively inhibits nitric oxide synthase. Further, it is used in immunology for detection of alkaline phosphatase. In addition to this, it acts as an oxidant.

Notes

Light sensitive. Store in a cool place. Incompatible with strong oxidizing agents.

Literature References

Materska, M.; Konopacka, M.; Rogoliński, J.; Ślosarek, K. Antioxidant activity and protective effects against oxidative damage of human cells induced by X-radiation of phenolic glycosides isolated from pepper fruits Capsicum annuum L. Food Chem. 2015, 168, 546-553.

Xiong, B.; Xu, R.; Zhou, R.; He, Y.; Yeung, E. S. Preventing UV induced cell damage by scavenging reactive oxygen species with enzyme-mimic Au-Pt nanocomposites. Talanta 2014, 120, 262-267.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P301+P312-P312-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
4115923
Harmonized Tariff Code
2933.99
TSCA
Yes
RTECS
XF8045000

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