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207738-08-7 - 3,3',5,5'-Tetramethylbenzidine dihydrochloride hydrate, 98% - TMB dihydrochloride hydrate - J60332 - Alfa Aesar

J60332 3,3',5,5'-Tetramethylbenzidine dihydrochloride hydrate, 98%

CAS Number
TMB dihydrochloride hydrate

Size Price ($) Quantity Availability
1g 42.88
2.5g 85.26
5g 143.38
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3,3',5,5'-Tetramethylbenzidine dihydrochloride hydrate, 98%


Chemical Properties

Formula Weight
Moisture & Light Sensitive
Soluble in DMSO (~1.7 mg/ml), and 1:300 DMSO:PBS (pH 7.2) (0.03 mg/ml).


3,3',5,5'-Tetramethylbenzidine dihydrochloride hydrate is a chromophore substrate in ELISA assays. It is a noncarcinogenic substitute for benzidine.


Moisture and light sensitive. Store away from oxidizing agents, heat, light, acids, water/ moisture.

Literature References

Sarah Gerlo; Peggy Verdood; Birgit Gellersen; Elisabeth L. Hooghe-Peters and Ron Kooijman. Mechanism of Prostaglandin (PG)E2-Induced Prolactin Expression in Human T Cells: Cooperation of Two PGE2 Receptor Subtypes, E-Prostanoid (EP) 3 and EP4, Via Calcium- and Cyclic Adenosine 5?-Monophosphate-Mediated Signaling Pathways. The Journal of Immunology.2004, 173 (10), 5952-5962.

Evemie Schutyser; Sofie Struyf; Patricia Menten; Jean-Pierre Lenaerts; René Conings; Willy Put; Anja Wuyts; Paul Proost and Jo Van Damme. Regulated Production and Molecular Diversity of Human Liver and Activation-Regulated Chemokine/Macrophage Inflammatory Protein-3α from Normal and Transformed Cells. The Journal of Immunology. 1973, 165 (8), 4470-4477.

GHS Hazard and Precautionary Statements

Hazard Statements: H341-H302-H315-H319

Suspected of causing genetic defects. Harmful if swallowed. Causes skin irritation. Causes serious eye irritation.

Precautionary Statements: P201-P280-P281-P305+P351+P338-P362-P301+P312-P308+P313-P321-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. Use personal protective equipment as required. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Take off contaminated clothing and wash before reuse. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF exposed or concerned: Get medical advice/attention. Specific treatment (see label). Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code


  • A12826

    3-Methoxyphenol, 97%
  • H56685

    Naphthalene-2-sulfonic acid, 98%
  • A12253

    Salicylic acid, 99%
  • H60057

    Methyl 4-vinylbenzoate, 97%
  • J66988

    [D-Arg<sup>1</sup>, D-Phe<sup>5</sup>, D-Trp<sup>7</sup><sup>,</sup><sup>9</sup>, Leu<sup>1</sup><sup>1</sup>] Substance P

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