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3,3',5,5'-Tetramethylbenzidine dihydrochloride hydrate is a chromophore substrate in ELISA assays. It is a noncarcinogenic substitute for benzidine.
Sarah Gerlo; Peggy Verdood; Birgit Gellersen; Elisabeth L. Hooghe-Peters and Ron Kooijman. Mechanism of Prostaglandin (PG)E2-Induced Prolactin Expression in Human T Cells: Cooperation of Two PGE2 Receptor Subtypes, E-Prostanoid (EP) 3 and EP4, Via Calcium- and Cyclic Adenosine 5?-Monophosphate-Mediated Signaling Pathways. The Journal of Immunology.2004, 173 (10), 5952-5962.
Evemie Schutyser; Sofie Struyf; Patricia Menten; Jean-Pierre Lenaerts; René Conings; Willy Put; Anja Wuyts; Paul Proost and Jo Van Damme. Regulated Production and Molecular Diversity of Human Liver and Activation-Regulated Chemokine/Macrophage Inflammatory Protein-3α from Normal and Transformed Cells. The Journal of Immunology. 1973, 165 (8), 4470-4477.
Hazard Statements: H302-H315-H319-H341
Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. Suspected of causing genetic defects.
Precautionary Statements: P201-P280-P305+P351+P338-P301+P312a-P405-P501a
Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.