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J60433 Carboplatin

CAS Number
41575-94-4
Synonyms
1,1-Cyclobutanedicarboxylatodiammineplatinum(II)
cis-Diammine(1,1-cyclobutanedicarboxylato) platinum

Stock No. Size Price ($) Quantity Availability
J60433-03 1g 370.00
J60433-06 5g 1111.00
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Carboplatin

MDL
MFCD00070464
EINECS
255-446-0

Chemical Properties

Formula
C6H12N2O4Pt
Formula Weight
371.25
Form
Powder
Storage & Sensitivity
Store at -20°C.
Solubility
Soluble in water.

Applications

Carboplatin is primarily used as an antitumor agent.Carboplatin is widely utilized as a chemotherapy drug to treat various types of cancer. It belongs to the group of platinum-based antineoplastic agents to interfere in DNA (deoxyribonucleic acid) repair. It is applied in combination other medications and used to inhibit cancer cell growth.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

Literature References

Jakacki, R. I.; Burger, P. C.; Kocak, M.; Boyett, J. M.; Goldwein, J.; Mehta, M.; Packer, R. J.; Tarbell, N. J.; Pollack, I. F. Outcome and Prognostic Factors for Children With Supratentorial PrimitiveNeuroectodermal Tumors Treated With Carboplatin During Radiotherapy:A Report from the Children’s Oncology Group. Pediatr Blood Cancer 2015, 62 (5), 776-783.

Boal, A. K.; Rosenzweig, A. C. Response from Boal and Rosenzweig to Crystallography and chemistry should always go together: a cautionary tale of protein complexes with cisplatin and carboplatin. Acta Crystallogr., Sect. D: Biol. Crystallogr. 2015, 71, 1984-1986.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H312-H317-H332-H334-H340-H350-H360

Harmful if swallowed. Harmful in contact with skin. May cause an allergic skin reaction. Harmful if inhaled. May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause genetic defects. May cause cancer. May damage fertility or the unborn child.

Precautionary Statements: P201-P202-P261-P264b-P270-P271-P272-P280g-P281-P285-P301+P312-P302+P352-P304+P340-P308+P313-P312-P330-P333+P313-P342+P311-P363-P501c

Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Contaminated work clothing should not be allowed out of the workplace. Wear protective gloves. Use personal protective equipment as required. In case of inadequate ventilation wear respiratory protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF exposed or concerned: Get medical advice/attention. Rinse mouth. If skin irritation or rash occurs: If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,1822
Harmonized Tariff Code
2843.90
TSCA
No
RTECS
TP2300000

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