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9039-53-6 - Urokinase, human urine - EC 3.4.21.73 - J60553 - Alfa Aesar

J60553 Urokinase, human urine

CAS Number
9039-53-6
Synonyms
EC 3.4.21.73

Size Price ($) Quantity Availability
100microg 111.20
1mg 288.40
5mg 1248.00
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Urokinase, human urine

MDL
MFCD00132566
EINECS
232-917-9

Chemical Properties

Form
Lyophilized powder, 54 kDa
Solubility
Reconstitute in water at 100µg/ml

Applications

Urokinase is used clinically as a thrombolytic agent in the treatment of severe or massive deep venous thrombosis, pulmonary embolism, myocardial infarction, and occluded intravenous or dialysis cannulas. It is also administered intrapleurally to improve the drainage of complicated pleural effusions and empyemas. Urokinase is a thrombolytic drug in infarction. Urokinase-plasminogen activator may be a new prognostic marker in breast cancer.

Notes

83,700IU/mg. 1nM UK will cause a change in absorbance of 0.001 at 405nm in 1 minute at R/T in 100 ul 0.05M Tris-HCl, 0.1M NaCl, pH 7.4, using S2444 (0.6mM) as the substrate

Literature References

Michael J. Duffy,; Liam O'siorain M,; James J. Fennelly. Urokinase-plasminogen activator, a marker for aggressive breast carcinomas. Preliminary report. Cancer. 1988, 62 (3),531-533,.

Stump DC,; Thienpont M,; Collen D.s. Urokinase-related proteins in human urine. Isolation and characterization of single-chain urokinase (pro-urokinase) and urokinase-inhibitor complex.. J Biol Chem. 1986, 261 (3), 1267-73.

Other References

Merck
14,9887
Harmonized Tariff Code
3507.90
TSCA
Yes
RTECS
OB8900000

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