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J60579 Doxycycline hyclate

CAS Number
24390-14-5
Synonyms
Hydramycin
Doxycycline hydrochloride hemiethanolate hemihydrate

Stock No. Size Price ($) Quantity Availability
J60579-14 25g 68.90
J60579-22 100g 231.00
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Doxycycline hyclate

MDL
MFCD07357237

Chemical Properties

Formula
C22H24N2O8•HCl.0.5H2O.0.5C2H6O
Formula Weight
512.94 (503.94anhy)
Form
Powder
Storage & Sensitivity
Keep Cold.
Solubility
Soluble in water to 50mg/ml. May require warming.Soluble in water, methanol. Sparingly soluble in ethanol. Insoluble in chloroform and ether.

Applications

Inhibits matrix metalloproteinases at subantimicrobial doses.Doxycycline hyclate is an antibacterial antibiotic, which is used in the treatment of chlamydia, rickettsia, mycoplasma and some spirochete infections. It is also used to inhibit matrix metalloproteinases at subantimicrobial doses.

Notes

Store in a cool place. Incompatible with strong oxidizing agents.

Literature References

Giannelli, A.; Ramos, R. A. N.; Traversa, D.; Brianti, E.; Annoscia, G.; Bastelli, F.; Dantas-Torres, F.; Otranto, D. Treatment of Dirofilaria repens microfilariaemia with a combination of doxycycline hyclate and ivermectin. Vet. Parasitol. 2013, 197 (3-4), 702-704.

Vijayabala, G. S.; Kalappanavar, A. N.; Annigeri, R. G.; Sudarshan, R.; Shettar, S. S. Single application of topical doxycycline hyclate in the management of recurrent aphthous stomatitis. Oral Surg. Oral Med Oral Pathol. Oral Radiol. 2013, 166 (4), 440-446.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H315-H319-H335-H361fd

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. Suspected of damaging fertility. Suspected of damaging the unborn child.

Precautionary Statements: P201-P202-P264b-P270-P271-P280i-P281-P301+P312-P302+P352-P304+P340-P305+P351+P338-P308+P313-P330-P332+P313-P362-P501c

Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear eye/face protection. Use personal protective equipment as required. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or concerned: Get medical advice/attention. Rinse mouth. If skin irritation occurs: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,3440
Harmonized Tariff Code
2941.30
TSCA
No
RTECS
QI8925000

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