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Inhibits matrix metalloproteinases at subantimicrobial doses.Doxycycline hyclate is an antibacterial antibiotic, which is used in the treatment of chlamydia, rickettsia, mycoplasma and some spirochete infections. It is also used to inhibit matrix metalloproteinases at subantimicrobial doses.
Giannelli, A.; Ramos, R. A. N.; Traversa, D.; Brianti, E.; Annoscia, G.; Bastelli, F.; Dantas-Torres, F.; Otranto, D. Treatment of Dirofilaria repens microfilariaemia with a combination of doxycycline hyclate and ivermectin. Vet. Parasitol. 2013, 197 (3-4), 702-704.
Vijayabala, G. S.; Kalappanavar, A. N.; Annigeri, R. G.; Sudarshan, R.; Shettar, S. S. Single application of topical doxycycline hyclate in the management of recurrent aphthous stomatitis. Oral Surg. Oral Med Oral Pathol. Oral Radiol. 2013, 166 (4), 440-446.
Hazard Statements: H302-H315-H319-H335
Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.