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24390-14-5 - Doxycycline hyclate - Hydramycin - Doxycycline hydrochloride hemiethanolate hemihydrate - J60579 - Alfa Aesar

J60579 Doxycycline hyclate

CAS Number
24390-14-5
Synonyms
Hydramycin
Doxycycline hydrochloride hemiethanolate hemihydrate

Size Price ($) Quantity Availability
25g 60.70
100g 204.00
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Doxycycline hyclate

MDL
MFCD07357237

Chemical Properties

Formula
C22H24N2O8•HCl.0.5H2O.0.5C2H6O
Formula Weight
512.94 (503.94anhy)
Form
Powder
Solubility
Soluble in water to 50mg/ml. May require warming.Soluble in water, methanol. Sparingly soluble in ethanol. Insoluble in chloroform and ether.

Applications

Inhibits matrix metalloproteinases at subantimicrobial doses.Doxycycline hyclate is an antibacterial antibiotic, which is used in the treatment of chlamydia, rickettsia, mycoplasma and some spirochete infections. It is also used to inhibit matrix metalloproteinases at subantimicrobial doses.

Notes

Store in a cool place. Incompatible with strong oxidizing agents.

Literature References

Giannelli, A.; Ramos, R. A. N.; Traversa, D.; Brianti, E.; Annoscia, G.; Bastelli, F.; Dantas-Torres, F.; Otranto, D. Treatment of Dirofilaria repens microfilariaemia with a combination of doxycycline hyclate and ivermectin. Vet. Parasitol. 2013, 197 (3-4), 702-704.

Vijayabala, G. S.; Kalappanavar, A. N.; Annigeri, R. G.; Sudarshan, R.; Shettar, S. S. Single application of topical doxycycline hyclate in the management of recurrent aphthous stomatitis. Oral Surg. Oral Med Oral Pathol. Oral Radiol. 2013, 166 (4), 440-446.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,3440
Harmonized Tariff Code
2941.30
TSCA
No
RTECS
QI8925000

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