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16676-29-2 - Naltrexone hydrochloride - J60590 - Alfa Aesar

J60590 Naltrexone hydrochloride

CAS Number
16676-29-2
Synonyms

Size Price ($) Quantity Availability
250mg 111.35
1g 486.16
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Naltrexone hydrochloride

MDL
MFCD00069324
EINECS
240-723-0

Chemical Properties

Formula
C19H21NO4•HCl
Formula Weight
377.86
Form
Powder
Sensitivity
Light Sensitive
Solubility
Soluble in water at 50mg/ml.

Applications

A congener of naloxone and also an opioid antagonist.Naltrexone hydrochloride is used in the treatment of alcohol and utilized for deceasing drinking habit. It is also used to prevent euphorigenic effects in the treatment of patients addicted to opioids. Further, it is used as a specific opiate antagonist.

Notes

Light sensitive. Incompatible with bases and oxidizing agents. Store in a cool place.

Literature References

Abdelkader, H.; Pierscionek, B.; Alany, R. G. Novel in situ gelling ocular films for the opioid growth factor-receptor antagonist-naltrexone hydrochloride: fabrication, mechanical properties, mucoadhesion, tolerability and stability studies. Int. J. Pharm. 2014, 477 (1-2), 631-642.

Darwish, M.; Bond, M.; Yang, R.; Tracewell, W.; Robertson J, P. Assessment of Alcohol-Induced Dose Dumping with a Hydrocodone Bitartrate Extended-Release Tablet Formulated with CIMA Abuse Deterrence Technology. Clin. Drug Invest. 2015, 35 (10), 645-652.

GHS Hazard and Precautionary Statements

Hazard Statements: H302

Harmful if swallowed.

Precautionary Statements: P264-P270-P301+P312-P330-P501a

Wash thoroughly after handling. Do not eat, drink or smoke when using this product. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Rinse mouth. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,6363
Beilstein
3580333
Harmonized Tariff Code
2939.19
TSCA
No
RTECS
QD2160000

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