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J60594 Fasudil dihydrochloride, 99+%

CAS Number
203911-27-7
Synonyms
HA-1077 dihydrochloride

Stock No. Size Price ($) Quantity Availability
J60594-MD 250mg 184.00
J60594-ME 500mg 322.00
J60594-03 1g 623.00
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Fasudil dihydrochloride, 99+%

MDL
MFCD00153805

Chemical Properties

Formula
C14H17N3O2S•2HCl
Formula Weight
364.29
Form
Powder
Storage & Sensitivity
Store at -20°C.
Solubility
Soluble in water and dimethylsulfoxide.

Applications

Fasudil dihydrochloride is used in the inhibition of contractile responses to potassium chloride, phenylephnne (PHE), prostaglandin and hepatic stellate cells spreading. It is also used in the formation of stress fibers and in medicine.

Notes

Incompatible with strong oxidizing agents. Sore in a cool place.

Literature References

Zeng, P.; Pi, R.; Li, P.; Chen, R.; Lin, L.; He, H.; Zhou, S. Fasudil hydrochloride, a potent ROCK inhibitor, inhibits corneal neovascularization after alkali burns in mice. Mol. Vis. 2015, 21, 688-698.

Ichikawa, M.; Yoshida, J.; Saito, K.; Sagawa, H.; Tokita, Y.; Watanabe, M. Differential effects of two ROCK inhibitors, Fasudil and Y-27632, on optic nerve regeneration in adult cats. Brain Res. 2008, 1201, 23-33.

Other References

Merck
14,3942
Harmonized Tariff Code
2935.90
TSCA
No
RTECS
HM4031166

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