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203911-27-7 - Fasudil dihydrochloride, 99+% - HA-1077 dihydrochloride - J60594 - Alfa Aesar

J60594 Fasudil dihydrochloride, 99+%

CAS Number
203911-27-7
Synonyms
HA-1077 dihydrochloride

Size Price ($) Quantity Availability
250mg 184.00
500mg 321.00
1g 623.00
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Fasudil dihydrochloride, 99+%

MDL
MFCD00153805

Chemical Properties

Formula
C14H17N3O2S•2HCl
Formula Weight
364.29
Form
Powder
Solubility
Soluble in water and dimethylsulfoxide.

Applications

Fasudil dihydrochloride is used in the inhibition of contractile responses to potassium chloride, phenylephnne (PHE), prostaglandin and hepatic stellate cells spreading. It is also used in the formation of stress fibers and in medicine.

Notes

Incompatible with strong oxidizing agents. Sore in a cool place.

Literature References

Zeng, P.; Pi, R.; Li, P.; Chen, R.; Lin, L.; He, H.; Zhou, S. Fasudil hydrochloride, a potent ROCK inhibitor, inhibits corneal neovascularization after alkali burns in mice. Mol. Vis. 2015, 21, 688-698.

Ichikawa, M.; Yoshida, J.; Saito, K.; Sagawa, H.; Tokita, Y.; Watanabe, M. Differential effects of two ROCK inhibitors, Fasudil and Y-27632, on optic nerve regeneration in adult cats. Brain Res. 2008, 1201, 23-33.

GHS Hazard and Precautionary Statements

Precautionary Statements: P260u-P201-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,3942
Harmonized Tariff Code
2935.90
TSCA
No
RTECS
HM4031166

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